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Tóm tắt
Mục tiêu nghiên cứu nhằm đánh giá tác động của synbiotic gồm Bacillus sp. và fructooligosaccharide (FOS) trong khẩu phần ăn đối với một số chỉ tiêu tăng trưởng và miễn dịch của cá nâu (Scatophagus argus). Thí nghiệm được bố trí ngẫu nhiên với bốn nghiệm thức, lặp lại 3 lần, bao gồm: Đối chứng (NT1, không bổ sung Bacillus sp. + FOS vào thức ăn), NT2 (Bacillus sp. 10⁷ CFU/mL), NT3 (Bacillus sp. 10⁷ CFU/mL + 0,2% FOS) và NT4 (Bacillus sp. 10⁷ CFU/mL + 0,5% FOS). Cá thí nghiệm được thu mẫu để xác định các chỉ tiêu tăng trưởng tại ngày 0 và ngày 60; tổng số hồng cầu và hoạt tính enzyme lysozyme tại ngày 30 và 60; và cảm nhiễm với Vibrio sp. sau 60 ngày cho ăn thức ăn thử nghiệm. Kết quả cá ở nghiệm thức NT3 và NT4 ghi nhận tốc độ tăng trưởng, tổng số hồng cầu và hoạt tính lysozyme cao hơn rõ rệt so với cá ở nghiệm thức đối chứng. Các chỉ số này tăng có ý nghĩa thống kê (p<0,05) ở các nghiệm thức bổ sung Bacillus sp. + FOS vào thức ăn. Sau khi cảm nhiễm Vibrio sp., cá ở nghiệm thức NT4 có tỷ lệ chết tích lũy 30% được ghi nhận thấp nhất so với cá ở các nghiệm thức khác. Kết quả khẳng định hiệu quả tích cực của synbiotic Bacillus sp. – FOS đối với tăng trưởng và sức kháng bệnh của cá nâu.
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Nguyễn Thị Huế Linh, Nguyễn Đức Quỳnh Anh, Nguyễn Thị Xuân Hồng, & Nguyễn Ngọc Phước. (2026). Ảnh hưởng của synbiotic Bacillus sp. - fructooligosaccharide đến các chỉ tiêu tăng trưởng và một số yếu tố kháng bệnh của cá nâu (Scatophagus argus). Tạp Chí điện tử Khoa học Và công nghệ nông nghiệp, 10(3), 5816–5826. https://doi.org/10.46826/huaf-jasat.v10n3y2026.1363
Chuyên mục
CHĂN NUÔI - THÚ Y- THỦY SẢN - ĐỘNG VẬT
Bản quyền @ 2017-2026 bởi Tạp chí điện tử Khoa học và công nghệ nông nghiệp
Tài liệu tham khảo
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Nguyễn Văn Huy, Lê Minh Tuệ, Trần Thị Thu Sương, Nguyễn Phi Nam, Lê Thị Thu An và Nguyễn Tử Minh. (2021). Đặc điểm dinh dưỡng và sinh trưởng của cá nâu Scatophagus argus (Linnaeus, 1776) phân bố ở đầm phá Tam Giang. Tạp chí Khoa học Đại học Cần Thơ, 57(2B), 162‒168. DOI: https://doi.org/10.22144/ctu.jvn.2021.050
Akrami, R., Iri, Y., Rostami H.K., & Mansour, M.R. (2013). Effect of dietary supplementation of fructooligosaccharide (FOS) on growth performance, survival, lactobacillus bacterial population and hematoimmunological parameters of stellate sturgeon (Acipenser stellatus) juvenile. Fish & Shellfish Immunology, 35, 1235‒1239.
Aly, S.M., Ahmed, Y.A.G., Ghareeb, A.A.A., & Mohamed, M.F. (2008). Studies on Bacillus subtilis and Lactobacillus acidophilus, as potential probiotics, on the immune response and resistance of tilapia nilotica (Oreochromis niloticus) to challenge infections. Fish & Shellfish Immunology, 25(1‒2), 128‒136. DOI: https://doi.org/10.1016/j.fsi.2008.03.013
Blancheton, J.P., Attramadal, K.J.K., Michaud, L., Roque d′ Orbcastel, E., & Vadstein, O. (2013). Insight into bacterial population in aquaculture systems and its implication. Aquacultural Engineering, 53, 30–39. DOI: https://doi.org/10.1016/j.aquaeng.2012.11.009
Chat, T.T, Anh, L.T.N, Huy, N.D, Hoa, T.T, Phat, L.T, Bossier, P. & Manh, H.N. (2024). Synbiotics of Pediococcus pentosaceus and fructooligosaccharide enhances the growth rate, enzymatic digestion, feed efficiency, hematological profiles, and lysozyme activity of Golden Rabbitfish (Siganus guttatus). Aquaculture Reports, 36, 102176. DOI: https://doi.org/10.1016/j.aqrep.2024.102176
De Vrese, M., & Schrezenmeir, J. (2008) Probiotics, prebiotics, and synbiotics. In: Food Biotechnology (pp. 1 - 66). Springer Berlin Heidelberg.
Dong, C., & Wang, J. (2013). Immunostimulatory effects of dietary fructooligosaccharides on red swamp crayfish, Procambarus clarkii (Girard). Aquaculture Research, 44(9), 1416‒1424.
Egerton, S., Culloty, S., Whooley, J., Stanton, C., & Ross, R.P. (2018). The gut microbiota of marine fish. Frontiers in Microbiology, 9. DOI: https://doi.org/10.3389/fmicb.2018.00873.
Ellis, A. E. (1990). Lysozyme Assays. In: Stolen, J.S., Fletcher, T.C., Anderson, D.P., Roberson, B.S. and Van Muiswinkel, W.B., Eds., Techniques in Fish Immunology, SOS Publications, Fair Haven, 101‒103.
El-Son, M.A.M., Nofal, M.I., & Abdel-Latif, H.M.R. (2021). Co-infection of Aeromonas hydrophila and Vibrio parahaemolyticus isolated from diseased farmed striped mullet (Mugil cephalus) in Manzala, Egypt – a case report. Aquaculture, 530, 735‒738.
Faramazi, M.S., Lashkarbolooki M., & Iranshahi F. (2011). The investigation of Lactobacillus acidophilus as probiotics on growth performance and disease resistance of rainbow trout (Oncorhychus mykiss). American-Eurasian Journal of Scientific Research, 6(1), 32‒38.
Guilherme, S.T., Ranzani-Paiva, M.J., Dias, D.C., Sussel, F.R., Ishikawa, C.M., & Tachibana, L. (2014). Dietary administration of Bacillus subtilis on hematology and nonspecific immunity of Nile tilapia Oreochromis niloticus raised at different stocking densities. Fish & Shellfish Immunology, 39(2), 305‒311.
Huynh, T.G., Shiu, Y.L., Nguyen, T.P., Truong, Q.P., Chen, J.C., & Liu, C.H. (2017). Current applications, selection, and possible mechanisms of actions of synbiotics in improving the growth and health status in aquaculture: A review. Fish & Shellfish Immunology, 64, 367‒382.
Ina-Salwany, M.Y., Al-saari, N., Mohamad, A., Mursidi, F.A., Mohd-Aris, A., Amal, M.N. A., Kasai, H., Mino, S., Sawabe, T., & Zamri-Saad, M. (2019). Vibriosis in fish: a review on disease development and prevention. The Journal of Aquatic Animal Health, 31, 3–22.
Lie O., Evensen O., Sorensen A., & Froysadal E. (1989). Study of lysozyme activity in some fish species. Diseases of Aquatic Organisms, 6, 1‒5.
Linda, S.S., Islam, Md. J., Mou, S.A., Islam, Md. H., Shahjahan, Md., & Islam, M.S. (2025). Synbiotic supplementation boosts growth, gut health, and immunity in Asian Fossil catfish (Heteropneustes fossilis), Aquaculture Research, 4542077. DOI: https://doi.org/10.1155/are/4542077
Maita, M. (2007). Fish health assessment. In: Nakagawa H., Sato M., Gatlin III D.M. (Eds.). Dietary supplements for the health and quality of cultured fish. CAB International. Oxon, UK, 10–34.
Maryam, K., & Masood, G. (2014). Studies on Bacillus subtilis, as potential probiotics, on the hematological and biochemical parameters of rainbow trout, Oncorhynchus mykiss (Walbaum). Journal of Applied & Environmental Microbiology, 2(5), 203‒207. DOI: https://doi.org/10.12691/jaem-2-5-1
Mohd Nor, N., Yazid, S.H.M., Daud, H.M., Amal, M.N.A., & Mohamad, N. (2019). Costs of management practices of Asian seabass (Lates calcarifer Bloch, 1790) cage culture in Malaysia using stochastic model that includes uncertainty in mortality. Aquaculture, 510, 347–352.
Mohd-Aris, A., Saad, M.Z., Daud, H.M., Yusof, M.T., & Ina-Salwany, M.Y. (2019). Vibrio harveyi protease deletion mutant as a live attenuated vaccine candidate against vibriosis and transcriptome profiling following vaccination for Epinephelus fuscoguttatus. Aquaculture International, 27, 125–140. DOI: https://doi.org/10.1007/s10499-018-0311-x
Natt, M.P., & Herrick, C.A. (1952). A new blood diluent for counting the erythrocytes and leucocytes of the chicken. Poultry Science, 31(4), 735‒738.
Panase, A., Thirabunyanon, M., Promya, J., & Chitmanat, C. (2023). Influences of Bacillus subtilis and fructooligosaccharide on growth performances, immune responses, and disease resistance of Nile tilapia, Oreochromis niloticus. Frontiers in Veterinary Science, 9, 1094681. DOI: 10.3389/fvets.2022.1094681.
Pandey, K. R, Naik, S. R., & Vakil, B. V. (2015). Probiotics, prebiotics and synbiotics- a review. Joural of Food Science and Technology, 52(12), 7577‒7587.
Pawar, N.A., Prakash, C., Kohli, M.S., Jamwal, A., Dalvi, R.S., Devi, B.N., Singh, S.K., Gupta, S., Lende, S.R., Sontakke, S.D., Gupta, S., & Jadhao, S.B. (2023). Fructooligosaccharide and Bacillus subtilis synbiotic combination promoted disease resistance, but not growth performance, is additive in fish. Scientific Report, 13, 11345. DOI: https://doi.org/10.1038/s41598-023-38267-7.
Peterman, M.A., & Posadas, B.C. (2019). Direct economic impact of fish diseases on the East Mississippi catfish industry. The North American Journal of Aquaculture, 81, 222–229.
Rahmi, Salam, N.I., Relatami, A.N.R., Anshar, A.R., Akmal, Syaichudin, M., Suwoyo, H.S., Mundayana, Y., Nisaa, K., Yani, F.I. and Muzalina, E. (2025). Effects of synbiotic supplementation on growth performance, hematological parameters and gut health in Nile Tilapia (Oreochromis niloticus). International Journal of Veterinary Science, 14(3), 470‒477.
Ransangan, J., Lal, T.M., & Al-Harbi, A.H. (2012). Characterization and experimental infection of Vibrio harveyi isolated from diseased Asian seabass (Lates calcarifer). Malaysian Journal of Microbiology, 8(2), 104–115.
Ringø, E., & Song, S. K. (2016). Application of dietary supplements (synbiotics and probiotics in combination with plant products and ß-glucans) in aquaculture. Aquaculture Nutrition, 22, 4‒24.
Sony, M., Sumithra, T.G., Anusree, V.N., Amala, P.V., Reshma, K.J., Alex, S., & Sanil, N.K. (2021). Antimicrobial resistance and virulence characteristics of Vibrio vulnificus, Vibrio parahaemolyticus and Vibrio harveyi from natural disease outbreaks of marine/estuarine fishes. Aquaculture, 539, 736608. DOI: https://doi.org/10.1016/j.aquaculture.2021.73660
Srirengaraj, V., Razafindralambo, H.L., Rabetafika, H.N., Nguyen, H.T., Sun, Y.Z. (2023). Synbiotic agents and their active components for sustainable aquaculture: Concepts, action mechanisms, and applications. Biology (Basel), 12(12), 1498. DOI: https://doi.org/10.3390/biology12121498
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